Makoto Noguchi
Professor in University of Toyama
Title: Optimal treatment of locally advanced squamous cell carcinoma based on tumor-related factors: staging, grading and responding
Biography
Biography: Makoto Noguchi
Abstract
Oral cancers arise in a major functional unit, the maxillo-oral region. Treatment of such cancers is aimed at preservation of form and function as well as radical cure. Aggressive treatment is associated with a higher rate of sever dysfunction. Therefore, optimal treatment suited to each individual case is very important in order to avoid overtreatment or oversurgery. The factors that influence choosing initial treatment are related to characteristics of the tumor (tumor-related factor), to the patient (host-related factors), and to environment of treatment (environment-related factors). Tumor-related factors are composed of clinical factors and pathological factors, including some biological information. In our efforts, initial therapeutic modalities have been selected based on tumor-related factors for optimization of treatment for individual case. I would like to present our treatment results for locally advanced oral squamous cell carcinoma.